Mouse Monoclonal Antibody to LPA
20294
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$308.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 8F6A9;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of LPA (4330-4521) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide. ;
MW: N/A
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=283
Reference: 1. J Stroke Cerebrovasc Dis. 2007 Sep-Oct;16(5):220-4. ; 2. Clin Chim Acta. 2008 Jan;387(1-2):109-12.
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