Mouse Monoclonal Antibody to FGR

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human,Mouse
Clone: 6G2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human FGR expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 56kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=299
Reference: 1. Immunity. 2005 Feb;22(2):235-46. ; 2. Biochemistry. 2007 Oct 2;46(39):11023-32.

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