Mouse Monoclonal Antibody to CSF1R

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. ; ; ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 6B9B9;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human CSF1R (AA: 344-497) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 108kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3550
Reference: 1. PLoS One. 2011;6(11):e27450. ; 2. J Biochem. 2012 Jan;151(1):47-55. ;

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