Mouse Monoclonal Antibody to CD68

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. ; ; ; ; ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 3F7D3;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human CD68 (AA: 42-155) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide.
MW: 37.4kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3582
Reference: 1. Rom J Morphol Embryol. 2012;53(1):61-6. ; 2. Anticancer Res. 2009 Aug;29(8):3269-79. ;

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