Mouse Monoclonal Antibody to ADD1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM:
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 5D4H1;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ADD1 (AA: 1-193) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 81kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3724
Reference: EMBO J. 2012 Mar 21;31(6):1453-66. ; Traffic. 2011 Oct;12(10):1327-40. ;

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