Mouse Monoclonal Antibody to RF1

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in directing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 4F9H12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human RF1 (AA: 288-437) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 49kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4114
Reference: 1.Nucleic Acids Res. 2013 Apr;41(8):4573-86. ; 2.Protein Sci. 2012 Jun;21(6):896-903.;

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