Anti-GATA3 Monoclonal Antibody

Anti-GATA3 Monoclonal Antibody

IHC583-100

Regular price $120.00 You Pay

Supplier: GenomeMe

Description:

GATA3 is a transcription factor important in cell proliferation, development, and differentiation. GATA3 is mostly observed in breast and urothelial carcinomas, and rarely present in other cancers such as endometrial endometrioid adenocarcinoma. Among the breast carcinomas, GATA3 has a lower expression in luminal B subtype breast carcinoma. Studies have found GATA3 expression to be associated with ER (estrogen receptor), PR (progesterone receptor), and Her2 in breast cancer cases. Urothelial carcinomas stain positively for GATA3 in invasive or high grade tumors, therefore Anti-GATA3 is useful for carcinoma diagnosis when breast and bladder are plausible.

Specifications:

Clone IHC583
Source Mouse Monoclonal
Positive Control

Breast Carcinoma, Urothelial Carcinoma

Dilution Range 1:100 - 1:400

Figure: GeneAbTM GATA3 [IHC583] on Breast Cancer

References

  1. Higgins JP, et al. Am J Surg Pathol. 2007; 31:673-80.
  2. Liu H, et al. Am J Clin Pathol. 2012; 138:57-64.