GeneAbTM Kappa [IHC610] on Ovary

Anti Kappa Monoclonal Antibody

IHC610-100

Regular price $20.00 You Pay

Supplier:  GenomeMe

Description:

Anti-Kappa recognizes surface immunoglobulin on normal and neoplastic B-cells, and has been indicated as a potential aid in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas, where the expression of a single light chain class is restricted. The determination of light chain ratio is critical in evaluating B-cell neoplasms, as the majority of B-cell lymphomas express either kappa or lambda light chains, while a mixture of kappa and lambda is characteristic of reactive proliferations. In paraffin-embedded tissue, Anti-Kappa displays strong staining of kappa-positive plasma cells, as well as cells that have absorbed exogenous immunoglobulins.

Specifications:
Clone IHC610
Source Mouse Monoclonal
Positive Control

Tonsil

Dilution Range 1:100 - 1:200
IFU & SDS:
References:
  1. Bray M, et al. Am J Clin Pathol. 1983; 80:526-8.
  2. Ashton-Key M, et al. Histopathology. 1996; 29:525-31.
  3. Kurtin PJ, et al. Am J Clin Pathol. 1999; 112:319-29.
  4. Falini B, et al. J Histochem Cytochem. 1982; 30:21-6.
  5. Marshall-Taylor CE, et al. Appl Immunohistochem Mol Morphol. 2002; 10:258-62.
  6. Sobol RE, et al. Clin Immunol Immunopathol. 1982; 24:139 -44.
  7. Samoszuk MK, et al. Diagn Immunol. 1985; 3:133-8.
  8. Abbondanzo SL, et al. Ann Diagn Pathol. 1999; 3:318-27.