GeneAbTM SALL4 [IHC659] on Testicular Cancer

Anti SALL4 Monoclonal Antibody

IHC659-100

$60.00 You Pay

Supplier:  GenomeMe

Description:

Sal-Like Protein 4 (SALL4), is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumors (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germ-cell tumors, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.

Specifications:
Clone IHC659
Source Mouse Monoclonal
Positive Control

Seminoma, Dysgerminoma
Dilution Range 1:100 - 1:200
IFU & SDS:
References:
  1. Ma Y, et al. Blood. 2006; 108:2726-35.
  2. de Celis JF, et al. Int J Dev Biol. 2009; 53:1385–98.
  3. Kohlhase J, et al. Hum Mutat. 2005; 26:176–83.
  4. Miettinen M, et al. Am J Surg Pathol. 2014; 38:410–20.
  5. Zhang X, et al. Cancer Lett. 2015; 357:55–62.
  6. Ueno S, et al. Exp Hematol. 2014; 42:307–16.
  7. Cao D, et al. Am J Surg Pathol. 2009; 33:1065–77.
  8. Zhang L, et al. Oncogene. 2014; 33:5491–500.
  9. Kobayashi D, et al. Int J Oncol. 2011; 38:933–9.
  10. Cui W, et. al. Mod Pathol. 2006; 19:1585-92.
  11. Cao D, et al. Am J Surg Pathol. 2009; 33:894-904.
Back to GenomeMe Products