MOG-Peptid (35-55) rat, mouse

Supplier: peptides&elephants GmbH
Product Type: peptide
Description: Myelin oligodendrocyte glycoprotein (MOG) 35-55, a minor component of CNS myelin,  is expressed in central nervous system myelin which produces a relapsing-remitting neurological diesease with extensive plague-like demyelination. It is believed to be a target autoantigen in multiple sclerosis. MOG 35-55 peptide is an immunodominant epitope of MOG that induces strong T and B cell responses and Induces experimental autoimmune encephalomyelitis in rodents. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. This Cysteine containing MOG (35-55) peptide can be use to induced polyclonal anti-MOG(35-55) antibody production in rabbits with high specificity, high affinity, and high titer indicating its high purity, as well as suitability for peptide-coated ELISA and Western blot assay. Immunization with MOG (35-55) suppresses spontaneous regeneration of dopaminergic neurons injured with MPTP. sterile and endotoxin free
Applications: Multiple Sclerosis: MOG 35-55 induced experimental autoimmune encephalomyelitis (EAE) rodent models
Sequence: H-MEVGWYRSPFSRVVHLYRNGK-OH
Amount: 2x1 mg
Purity (HPLC): > 95%
Form: lyophilized as powder
Storage: -20°C