Mouse Monoclonal Antibody to ATF2

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human; Mouse
Clone: 4F12;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human ATF2 expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 55kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=563
Reference: 1. J Dermatol Sci. 2008 Sep;51(3):210-5. ; 2. J Biol Chem. 2008 Jun 20;283(25):17605-14.

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