Recombinant Mouse Transforming Growth Factor ?-2/TGF?2/TGFB2 Protein

Supplier: Elabscience Product Name: Recombinant Mouse Transforming Growth Factor ?-2/TGF?2/TGFB2 Protein Catalog No. PKSM041168 Product Type: recombinant protein Size: 50 ug Activity: Protein Construction: Recombinant Mouse Transforming Growth Factor beta 2 is produced by our Mammalian expression system and the target gene encoding Ala303-Ser414 is expressed. Sequence: Ala303-Ser414 Fusion Tag: Accession: P27090 Species: Mouse Expressed Host: Human Cells Shipping Conditions: The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. Purity: ?95% as determined by reducing SDS-PAGE. Endotoxin: <1.0 EU per ?g as determined by LAL test. Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months Molecular Weight: 12.7 kDa Applied MM: 25-28 kDa Formulation: Lyophilized from a 0.2 ?m filtered solution of 4 mM HCl. Reconstitution: Please refer to the printed manual for detailed information. Background: Transforming growth factor beta 2 (TGF-?2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-?2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-? isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-? receptor type II (T?R-II), and a TGF-? receptor type I (T?R-I). Signal transduction from the receptor to the nucleus is mediated via SMADs. TGF-? expression is found in cartilage, bone, teeth, muscle, heart, blood vessels, haematopoitic cells, lung, kidney, gut, liver, eye, ear, skin, and the nervous system.