Recombinant Mouse Transglutaminase 2/TGM2 Protein(C-6His)
PKSM041171
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Supplier: Elabscience
Product Name: Recombinant Mouse Transglutaminase 2/TGM2 Protein(C-6His)
Catalog No. PKSM041171
Product Type: recombinant protein
Size: 50 ug
Activity:
Protein Construction: Recombinant Mouse Transglutaminase 2 is produced by our Mammalian expression system and the target gene encoding Ala2-Ala686 is expressed with a 6His tag at the C-terminus.
Sequence: Ala2-Ala686
Fusion Tag: C-6His
Accession: P21981
Species: Mouse
Expressed Host: Human Cells
Shipping Conditions: The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Purity: ?95% as determined by reducing SDS-PAGE.
Endotoxin: <1.0 EU per ?g as determined by LAL test.
Stability: Store at < -20?, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
Molecular Weight: 78.0 kDa
Applied MM: 70-80 kDa
Formulation: Supplied as a 0.2 ?m filtered solution of 20mM TrisHCl,150mM NaCl,20%Glycerol,pH7.5.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene.