Recombinant Mouse TREML2/TLT-2 Protein(C-6His)

Supplier: Elabscience Product Name: Recombinant Mouse TREML2/TLT-2 Protein(C-6His) Catalog No. PKSM041173 Product Type: recombinant protein Size: 50 ug Activity: Protein Construction: Recombinant Mouse Triggering Receptor Expressed on Myeloid Cells-like Protein 2 is produced by our Mammalian expression system and the target gene encoding His25-Ala270 is expressed with a 6His tag at the C-terminus. Sequence: His25-Ala270 Fusion Tag: C-6His Accession: Q2LA85 Species: Mouse Expressed Host: Human Cells Shipping Conditions: The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. Purity: ?95% as determined by reducing SDS-PAGE. Endotoxin: <1.0 EU per ?g as determined by LAL test. Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months Molecular Weight: 28.4 kDa Applied MM: 58-62 kDa Formulation: Lyophilized from a 0.2 ?m filtered solution of PBS, pH7.4. Reconstitution: Please refer to the printed manual for detailed information. Background: Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.