Recombinant Mouse ?-Synuclein/SNCA Protein

Supplier: Elabscience Product Name: Recombinant Mouse ?-Synuclein/SNCA Protein Catalog No. PKSM041187 Product Type: recombinant protein Size: 50 ug Activity: Protein Construction: Recombinant Mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed. Sequence: Met1-Ala140 Fusion Tag: Accession: O55042 Species: Mouse Expressed Host: E.coli Shipping Conditions: The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below. Purity: ?95% as determined by reducing SDS-PAGE. Endotoxin: <1.0 EU per ?g as determined by LAL test. Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months Molecular Weight: 14.5 kDa Applied MM: 17 kDa Formulation: Lyophilized from a 0.2 ?m filtered solution of PBS, pH7.4. Reconstitution: Please refer to the printed manual for detailed information. Background: Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).