Recombinant Mouse Complement factor D Protein

Supplier: Elabscience Product Name: Recombinant Mouse Complement factor D Protein Catalog No. PKSM041212 Product Type: recombinant protein Size: 50 ug Activity: Protein Construction: Recombinant Mouse Complement factor D is produced by our Mammalian expression system and the target gene encoding Ile26-Ser259 is expressed with a 6His tag at the C-terminus. Sequence: Ile26-Ser259 Fusion Tag: C-6His Accession: P03953 Species: Mouse Expressed Host: Human Cells Shipping Conditions: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Purity: ?95% as determined by reducing SDS-PAGE. Endotoxin: <1.0 EU per ?g as determined by LAL test. Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months Molecular Weight: 26.5 kDa Applied MM: 40-49 kDa Formulation: Lyophilized from a 0.2 ?m filtered solution of 20mMTris,150mMNaCl,pH7.5. Reconstitution: Please refer to it for detailed information. Background: Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the regulation of systemic energy balance and physiologic and pathologic processes, including immunity and inflammation.