Recombinant Mouse Interleukin-2 receptor subunit alpha Protein
PKSM041228
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Supplier: Elabscience
Product Name: Recombinant Mouse Interleukin-2 receptor subunit alpha Protein
Catalog No. PKSM041228
Product Type: recombinant protein
Size: 50 ug
Activity:
Protein Construction: Recombinant Mouse Interleukin-2 receptor subunit alpha is produced by our Mammalian expression system and the target gene encoding Glu22-Lys236 is expressed with a Fc tag at the C-terminus.
Sequence: Met 1-Lys 236
Fusion Tag: C-Fc
Accession: NP_032393.3
Species: Mouse
Expressed Host: Human Cells
Shipping Conditions: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Purity: ?95% as determined by reducing SDS-PAGE.
Endotoxin: <1.0 EU per ?g as determined by LAL test.
Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months
Molecular Weight: 55.5 kDa
Applied MM: 60-90kDa
Formulation: Lyophilized from a 0.2 ?m filtered solution of PBS, pH7.4.
Reconstitution: Please refer to it for detailed information.
Background: The interleukin 2 receptor alpha (IL2RA), also called CD25, is a type I transmembrane protein that presents on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is a member of cytokine receptors family that utilizes the common gamma chain subunit (?c). IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. IL2RA associates with IL2RB (CD122) to form a heterodimer that can act as a high-affinity receptor for IL-2.