Recombinant Mouse T-cell-specific surface glycoprotein CD28 Protein

Supplier: Elabscience Product Name: Recombinant Mouse T-cell-specific surface glycoprotein CD28 Protein Catalog No. PKSM041241 Product Type: recombinant protein Size: 50 ug Activity: Protein Construction: Recombinant Mouse T-cell-specific surface glycoprotein CD28 is produced by our Mammalian expression system and the target gene encoding Asn20-Lys149 is expressed with a Fc, 6His tag at the C-terminus. Sequence: Met 1-Lys 149 Fusion Tag: C-Fc-6His Accession: NP_031668.3 Species: Mouse Expressed Host: Human Cells Shipping Conditions: In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Purity: ?95% as determined by reducing SDS-PAGE. Endotoxin: <1.0 EU per ?g as determined by LAL test. Stability: Lyophilized protein should be stored at < -20?, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7? for 2-7 days.Aliquots of reconstituted samples are stable at < -20? for 3 months Molecular Weight: 43.0 kDa Applied MM: 60 kDa Formulation: Lyophilized from a 0.2 ?m filtered solution of 20mM PB,150mM NaCl,pH7.4. Reconstitution: Please refer to it for detailed information. Background: T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.