Mouse Monoclonal Antibody to GRIA3

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1D2;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human GRIA3 expressed in E. Coli. ;
Formulation: Ascitic fluid containing 0.03% sodium azide.
MW: 101kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=632
Reference: 1. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):468-76. ; 2. Am J Med Genet A. 2009 Jun;149A(6):1280-9.

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