Mouse Monoclonal Antibody to IGFBP7
30565
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$341.00
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Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). ;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 1D9E7;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human IGFBP7 (AA: 52-156) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 29.1kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=3526
Reference: 1. Sci Signal. 2012 Dec 18;5(255):ra92. ; 2. Cancer Biol Ther. 2012 Feb 1;13(3):148-55. ;
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