Mouse Monoclonal Antibody to SIRT6

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: ; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2G1H1;
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human SIRT6 (AA: 141-250) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 39kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4005
Reference: 1.Mol Med Rep. 2014 Mar;9(3):882-8. ; 2.Carcinogenesis. 2013 Jul;34(7):1476-86.;

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