Mouse Monoclonal Antibody to P2RX7

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.;
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; IHC: 1/200 - 1/1000; ICC: ; FCM: 1/200 - 1/400
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 7G1D6;
Isotype: Mouse IgG2b
Immunogen: Purified recombinant fragment of human P2RX7 (AA: 226-452) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 64.6kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4278
Reference: 1.Cancer Sci. 2015 Sep;106(9):1224-31. ; 2.J Hypertens. 2013 Dec;31(12):2362-9. ;

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