Mouse Monoclonal Antibody to BCL6

Supplier: ProMab Technologies
Type of Product: Monoclonal Antibody
Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
Application: ELISA: 1/10000; WB: 1/500 - 1/2000; ICC: 1/200 - 1/1000; FCM: 1/200 - 1/400; IHC: N/A
Size: 100 ul, 1mg/ml
Species Reactivity: Human
Clone: 2G1B6
Isotype: Mouse IgG1
Immunogen: Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
MW: 78.8kDa
Storage: 4C; -20C for long term storage
Supplier link: http://www.promab.com/index.php?main_page=product_info&products_id=4468
Reference: 1.Cancer Lett. 2015 Sep 1;365(2):190-200. 2.BMC Cancer. 2014 Jun 10;14:418.

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